Naltrexone For Weight Loss: Does it really help?

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Steven K. Pryor

Taking Naltrexone for weight loss can help you to achieve a healthy weight. Though it is not primarily used as a medicine for weight loss, it can help people to lose weight in the following ways. If you wanna know those ways, please keep reading.  

Naltrexone is used to treat patients suffering from drug and alcohol addiction. It is FDA approved medicine for addicts but also helps obese to reduce weight. A low dose of Naltrexone can help you to reduce weight along with a healthy lifestyle including calorie reduction, exercise, and healthy eating habits. 

Studies have shown that Naltrexone when combined with Bupropion gives the best results if you want to lose weight. These medicines have a great impact on eating behavior which helps in controlling appetite and many other ways to shed weight. 

Does Naltrexone works for Weight Loss?

Well, the exact answer to the above question is not clear yet. It has been seen that some patients benefit from that and others lack desired results. 

As discussed above Naltrexone helps appetite control and cravings which is a great cause of excess weight, so this medicine can help you to eat less which can prevent weight gain. But if you want to lose weight you need to take the combination of Naltrexone and Bupropion to have significant weight loss. 

Here are some ways by which Naltrexone helps to reduce weight:

  • Appetite Control

Naltrexone helps in appetite control. This way the medicine helps you to eat less, if you eat less you consume fewer calories which will help you to reduce weight.

For example: if you eat 2000 calories a day and burn 1500 calories then you are still high on calories. Here comes the role of Naltrexone which makes you consume less so you may have a lesser calorie count.

  • Anti Inflammatory

Naltrexone is an anti-inflammatory drug that reduces inflammation in the body. Inflammation can cause an increase in insulin resistance, hormonal imbalances, high estrogens, and thyroid. And these are the leading causes of weight gain. 

  • Improve Sleeping Patterns

People often comprise their sleep due to hectic schedules or late-night parties or maybe for some other reason. Inadequate sleep leads to inflammation and weight gain. Sleep apnea is one of the major reasons behind weight gain.

  • Increase Growth Hormone

Naltrexone also helps to increase growth hormone. An increase in growth hormone will lead to an increase in the fat-burning process that will finally help in weight loss. 

  • Thyroid Function 

Naltrexone helps in better Thyroid function. The thyroid can cause hormonal imbalances and an increase in insulin resistance that leads to excess weight. 

  • Boost Energy

Naltrexone boosts energy levels. If you have high energy levels then you can do more physical exercise and work that will surely help you to burn more calories and weight loss. 

  • Reduces Insulin Resistance

Insulin resistance is the primary cause of weight gain in many people. Patients with PCOS and hypothyroidism face the problem of insulin resistance. Thus Naltrexone helps in reducing insulin resistance and helps in weight loss. 

Naltrexone Weight Loss Side Effects

  • Nausea 
  • Vomiting
  • Diarrhea
  • Stomach Pain
  • Headache
  • Anxiety
  • Fever
  • Hallucinations
  • Discomfort while Urinating
  • Fever
  • Skin Rash
  • Swelling 
  • Shortness of breath
  • Muscle Pain
  • Chills
  • Constipation
  • Increased thirst
  • Irritability

Is naltrexone good for weight loss?

Naltrexone is not FDA approved medicine for weight loss. Though the combination of Naltrexone and Bupropion can give you the best results if you take it along with a healthy and balanced diet with an exercise routine. You should also check your calorie intake for significant weight loss. 

How much weight can you lose with Naltrexone?

You can Lose up to 5% of your body weight if you take Naltrexone. You should also follow a healthy diet and exercise plan along with the medication to get the best results. Medicine alone cannot help you in losing weight. 

How long does it take to lose weight on Naltrexone?

You can see the visible results after 4 weeks of medication. For some, it may take time as everyone’s body is different. You strictly need to take care of your calorie intake and exercise routine to get the best results. 

Bonus Tips:

  • Exercise everyday
  • Drink plenty of fluids
  • Adequate sleep
  • Have a colorful diet
  • Check on your calorie intake
  • Avoid outside and junk food
  • Stay active throughout the day
  • Eat-in small portions
  • Cut down alcohol and caffeine 
  • Cut down sugar from your diet

Conclusion on Naltrexone for Weight Loss 

Naltrexone is not primarily used as a medicine for weight loss. But it can help you to lose weight if you take along with a strict diet and workout. Studies have shown that some people benefit from it and some do not due to different health conditions. It also has side effects, do consult your doctor before starting it. The best way to lose weight is a healthy lifestyle which includes exercise, healthy eating habits, and meditation. If you like the article please like, share, and follow us. Till then bye! Stay safe! 


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